Adverse Drug Reaction Classification System

ADR Ontology
ADR Term Pyrexia
ADR ID BADD_A03683
ADR Hierarchy
08      General disorders and administration site conditions
08.05      Body temperature conditions
08.05.02      Febrile disorders
08.05.02.003      Pyrexia
Description An abnormal elevation of body temperature, usually as a result of a pathologic process. [MeSH]
MedDRA Code 10037660
MeSH ID D005334; D005334; D005334; D005334; D005335
ADR Severity Grade (FAERS)
ADR Severity Grade (CTCAE)
Synonym
Chills & fever | Chills and fever | Drug fever | Febrile reaction | Fever | Fever chills | Fever of unknown origin | Heat production increased | Heat retention | High temperature | Intermittent pyrexia | Periodic fever | PUO | Pyrexia | Pyrexia abnormal | Pyrexia drug | Pyrexia NOS | Pyrexia of unknown origin | Pyrexia of unknown origin (excl puerperal) | Pyrexial | Reaction febrile | Slight fever | Spiking temperature | Slight temperature | Intermittent fever | Cotton fever | Febricula | Fluctuating fever | Chronic fever | Acute febrile illness | Feverish | Pyrogenic reaction | Fevers | Pyrexias | Hyperthermia | Hyperthermias
ADR Related Proteins
Protein Name UniProt AC TTD Target ID
Alanine aminotransferase 2Q28DB5Not Available
Alkaline phosphatase, placental typeP05187Not Available
Glutathione hydrolase 1 proenzymeP19440Not Available
Drugs Leading to the ADR
Drug IDDrug NameADR Frequency (FAERS)ADR Severity Grade (FAERS)
BADD_D00475Citalopram--
BADD_D00476Citalopram hydrobromide--
BADD_D00479Cladribine0.002554%
BADD_D00480Clarithromycin0.030435%
BADD_D00483Clindamycin0.000201%
BADD_D00488Clobazam0.004214%
BADD_D00490Clobetasol propionate0.000532%
BADD_D00495Clofarabine0.001332%
BADD_D00498Clomiphene citrate--
BADD_D00499Clomipramine0.008855%
BADD_D00500Clomipramine hydrochloride--
BADD_D00501Clonazepam--
BADD_D00502Clonidine--
BADD_D00503Clonidine hydrochloride--
BADD_D00504Clopidogrel--
BADD_D00505Clopidogrel bisulfate--
BADD_D00507Clorazepic acid0.004718%
BADD_D00509Clotrimazole0.000689%
BADD_D00511Clozapine0.936002%
BADD_D00513Cobimetinib0.000799%
BADD_D00516Codeine--
BADD_D00523Colistimethate--
BADD_D00524Colistimethate sodium--
BADD_D00527Conivaptan hydrochloride--
BADD_D00528Conjugated estrogens--
BADD_D00531Corticotropin--
BADD_D00533Cortisone acetate0.021466%
BADD_D00535Crizotinib--
BADD_D00545Cyclobenzaprine--
BADD_D00547Cyclopentolate0.018703%
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